In this study，we aimed to overcome the mismatch between the response time and frame rate of liquid crystal display(LCD)and consider the performance of the LCD driver circuit. To this end，we designed an LCD driver circuit with automatic frame rate adjustment and excellent performance parameters based on the CSMC 0. 18 μm CMOS process. The proposed design employs a bandgap reference with a low dropout linear regulator to output a reference voltage with good temperature characteristics. Furthermore，it utilizes MOS tubes to control the gate and substrate voltages of the charge pump multiplier chain. This effectively reduces the reverse leakage current and efficiently outputs the required driving voltage for the LCD. Simultaneously，it utilizes the temperature measurement circuit and an 8-bit progressive analog-to-digital converter to control the clock frequency and achieve the frame rate self-adjustment function，thereby attenuating the LCD response time based on the impact of temperature changes. The measured results indicate that the maximum change of the reference voltage is 2. 6 mV in the temperature interval of .40 to 88 ℃，the charge pump boost efficiency is up to 93. 08%，and the adaptive frame rate adjustment range is 5– 150 Hz.